Creatine monohydrate improved cycling Wingate performance but not cognitive function in young active males and females
Silva JV, Nunes Oliveira T, Sampaio P, de Sousa Sá OM, Barreto G, Roschel H, Saunders B
Research in sports medicine (Print) · 0 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Government
- São Paulo Research Foundation
- Grants
- Fundação de Amparo à Pesquisa do Estado de São Paulo (Gabriel Barreto (2020/12036-3)); Fundação de Amparo à Pesquisa do Estado de São Paulo (OMSS (2022/04211-5)); Fundação de Amparo à Pesquisa do Estado de São Paulo (21/06836-0); Fundação de Amparo à Pesquisa do Estado de São Paulo (Tamires Nunes Oliveira (2022/07327-4)); Fundação de Amparo à Pesquisa do Estado de São Paulo (João Vitor Silva (PIBIC: 143595/2021-0))
Based on 2 listed funder(s).
Publication
- Published
- 2026-04-10 · Res Sports Med · vol. 34 · issue 5 · pp. 575–589
- Publisher
- Taylor & Francis
- Cited
- 0 citations · more than 26% of similar papers · 0.0× the field average
- References
- 37 works
- Access
- Paywalled
- Research areas
- Muscle metabolism and nutrition · Exercise and Physiological Responses · Thermoregulation and physiological responses
- Keywords
- Wingate test, Stroop effect, Placebo, Cognition, Cycling, Affect (linguistics), Effects of sleep deprivation on cognitive performance, Creatine
- MeSH
- humans, creatine, exercise test, double-blind method, cognition, bicycling, dietary supplements, adult, female, male, athletic performance, young adult, cognitive enhancement
7 authors
From BR, GB
- João Vitor SilvaUniversidade de São Paulo
- Tamires Nunes OliveiraUniversidade de São Paulo
- Priscilla SampaioUniversidade de São Paulo
- Odara Maria de Sousa SáUniversidade de São Paulo
- Gabriel Castanho BarretoUniversidade de São Paulo; University of Bristol
- Hamilton RoschelUniversidade de São Paulo
Abstract
This study evaluated the effects of creatine monohydrate (Cr) supplementation on cognitive and physical performance of young, healthy, omnivorous and physically active individuals, before and after high-intensity exercise. Forty healthy volunteers (20 males [age 23 ± 5 y] and 20 females [age 24 ± 5 y]) completed three visits comprising a familiarization to all test procedures, followed by 2 main trials separated by 1 week of 20 g/day Cr or placebo (maltodextrin) supplementation in a parallel-group design. Participants performed the Stroop Colour and Word Test 1 and 2 and Trail Test A and B pre- and post- a 30-s Wingate cycling test. Cr improved mean (pre-supplementation: 526 W; 95% CI: 510,542; vs. post-supplementation: 570 W; 95% CI: 554,586; p = 0.002; Effect size [ES]=0.94) and peak (pre-supplementation: 738 W; 95% CI: 684,791; vs. post-supplementation: 797 W; 95% CI: 743,850; p = 0.002; ES = 0.91) power output, with no sex differences shown. There were no effects of Cr on any of the cognitive tasks. Cr supplementation improved 30-s Wingate performance but did not affect cognitive performance. These data suggest that Cr may be beneficial for those involved in explosive exercise bouts. There appeared to be a learning effect for several of the cognitive tests, which may have masked any effect with Cr.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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