Study2026

Repeated low-level red light therapy for pathologic myopia: a case series of two adult patients

Zhang J, Zou Y, Zhang H, Zou H, Xu Y

The British journal of ophthalmology · 0 citations

How it was studied

Design
Case report (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
Government
Shanghai Municipal Health Commission
Government
China Postdoctoral Science Foundation
Government
Science and Technology Commission of Shanghai Municipality
University or hospital
Shanghai Hospital Development Center
Grants
Science and Technology Commission of Shanghai Municipality (No.24YF2740300); Shanghai Municipal Health Commission (No.202540067); Shanghai Hospital Development Center (No.SHDC12025102); China Postdoctoral Science Foundation (No.GZB20250556)

Based on 4 listed funder(s).

Publication

Published
2026-06-19 · Br J Ophthalmol · pp. bjo–2025
Publisher
BMJ
Cited
0 citations · more than 54% of similar papers · 0.0× the field average
References
15 works
Access
Open access (hybrid journal) · CC-BY-NC
Research areas
Ophthalmology and Visual Impairment Studies · Laser Applications in Dentistry and Medicine · Corneal surgery and disorders
Keywords
Visual acuity, Red light, Clinical trial, Light therapy, Randomized controlled trial, Macular degeneration

5 authors

From CN

  • Juzhao ZhangTongji University; Shanghai Eye Disease Prevention & Treatment Center
  • 邹月兰Shanghai Eye Disease Prevention & Treatment Center
  • H ZhangZoucheng People's Hospital
  • Haidong Zou · correspondingTongji University; Shanghai Eye Disease Prevention & Treatment Center
  • Yan Xu · correspondingTongji University; Shanghai Eye Disease Prevention & Treatment Center

Abstract

Pathologic myopia (PM) is a leading, traditionally irreversible cause of vision loss primarily managed through observation. This pilot case series explores repeated low-level red light (RLRL) therapy for PM. Two adult patients underwent twice-daily home-based RLRL sessions for 6 months. Preliminary observations revealed functional improvement in visual acuity for one patient, while the other demonstrated modest anatomical recovery, including reduced macular retinoschisis and slightly decreased axial length. These hypothesis-generating findings suggest RLRL might offer structural and functional benefits. However, rigorous future randomised controlled trials remain essential to validate its clinical efficacy.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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