Meta-analysis2026Open access

Caffeine makes a splash: a systematic review and multilevel meta-analysis exploring the effects of caffeine intake on swimming performance

Wang Z, Qiu B, Bao J, Diao P, Hamlin M, Del Coso J, Grgic J, Petersen C

Journal of the International Society of Sports Nutrition · 0 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2026-06-21 · J Int Soc Sports Nutr · vol. 23 · issue 1 · p. 2692016
Publisher
Springer Science+Business Media
Cited
0 citations · more than 48% of similar papers · 0.0× the field average
References
43 works
Access
Open access (journal) · CC-BY
Research areas
Coffee research and impacts · Muscle metabolism and nutrition · Pharmacology and Obesity Treatment
Keywords
Caffeine, Clinical nutrition, Sports medicine, MEDLINE, Alternative medicine
MeSH
humans, lactic acid, caffeine, swimming, randomized controlled trials as topic, athletic performance

8 authors

From NZ, CN, ES, HK

  • Ziyu WangUniversity of Canterbury
  • Bopeng QiuTsinghua University
  • Jinxuan BaoBeijing Sport University
  • Penglin DiaoWuhan Sports University
  • Michael J. Hamlin
  • Juan Del CosoUniversidad Rey Juan Carlos; Universidad Francisco de Vitoria

Abstract

Background

Evidence for acute caffeine supplementation in swimming remains inconsistent across reviews, likely due to between-study heterogeneity and methodological differences.

Methods

Five databases were searched for randomized placebo-controlled crossover trials exploring the effects of caffeine on swimming performance in competitive swimmers. Performance outcomes were pooled as standardized mean differences (SMD; Hedges' g), with time outcomes sign-reversed so that positive values indicated improved performance. Dependence among multiple outcomes within studies was addressed using three-level random-effects models (REML). As a supplementary, interpretable metric, log ratios of means (lnRoM) were meta-analysed and expressed as percentage change. Post-exercise blood lactate (mmol/L) was pooled as mean differences (MD). Risk of bias was assessed using RoB 2 and certainty of evidence using GRADE. Prespecified exploratory moderator analyses examined potential effect modification (dose, timing, distance, administration form, stroke, gender, and athlete level).

Results

Thirteen studies were included (144 men and 48 women), which contributed 28 performance effect sizes. Caffeine improved swimming performance (SMD = 0.57, 95% CI: 0.20 to 0.94; p = 0.005), corresponding to a +1.71% improvement in lnRoM (95% CI: +1.01% to +2.41%; p total = 64.7%) and primarily between studies. Eight studies contributed 24 blood lactate effect sizes. In the meta-analysis, caffeine increased post-test lactate (MD = 0.85 mmol/L, 95% CI: 0.22 to 1.49; p = 0.016) with high heterogeneity (I²total = 76.5%). Exploratory moderator analyses suggested a possible dose-related pattern for swimming performance, with larger pooled effects at ≥6 mg/kg (SMD = 0.95, 95% CI: 0.52 to 1.38) than at p difference = 0.017). Other performance moderators did not show clear between-subgroup differences. For lactate, exploratory subgroup analyses suggested larger increases in freestyle and short-distance events, although these patterns were more sensitive to modelling assumptions and should be interpreted cautiously.

Conclusion

Acute caffeine ingestion confers a moderate ergogenic benefit for swimming performance (SMD = 0.57, 1.7% improvement) and is associated with higher post-test blood lactate (MD = 0.85 mmol/L). Dose (≥6 mg/kg) may be associated with larger performance benefits, whereas lactate responses appear more pronounced in freestyle and shorter events. However, these subgroup findings are hypothesis-generating and require exploration.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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