Study2026

Comparison of posterior scleral reinforcement surgery and repeated low-level red-light therapy in controlling high and super high myopia in Chinese children

Ma SY, Yang MY, Fu AC, Meng J, Li XJ

International journal of ophthalmology · 0 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Controlled clinical trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2026-06-16 · Int J Ophthalmol · vol. 19 · issue 7 · pp. 1357–1365
Publisher
Press of International Journal of Ophthalmology (IJO PRESS)
Cited
0 citations · more than 54% of similar papers · 0.0× the field average
References
0 works
Access
Open access (journal) · CC-BY-NC-ND
Research areas
Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Ocular Surface and Contact Lens
Keywords
Reinforcement, Visual acuity, Subgroup analysis, Reduction (mathematics), Adverse effect

4 authors

From CN

  • Si-Yu MaFirst Affiliated Hospital of Zhengzhou University
  • Aicun FuFirst Affiliated Hospital of Zhengzhou University
  • Jia MengFirst Affiliated Hospital of Zhengzhou University
  • Xiu-Juan LiFirst Affiliated Hospital of Zhengzhou University

Abstract

Aim

To compare the efficacy of posterior scleral reinforcement (PSR) surgery versus repeated low-level red light therapy (RLRL) treatment in controlling high and super high myopia (HM and SHM) of Chinese children.

Methods

This retrospective case analysis enrolled Chinese children with HM (-6.00 to -10.00 D; 76 children, 120 eyes) or SHM (<-10.00 D; 82 children, 114 eyes) according to spherical equivalent (SE). Each group was further subdivided into PSR subgroup [single-vision spectacle lenses (SVS) combined with PSR surgery], RLRL subgroup (SVS combined with RLRL therapy), and control subgroup (SVS alone). All participants were followed up at baseline, 3mo, 1, and 2y after treatment. The best corrected visual acuity (BCVA), axial length (AL), SE, and adverse reactions were evaluated.

Results

A total of 158 children (234 eyes) aged 6-16y were enrolled consecutively. Baseline BCVA, AL and SE were comparable among subgroups in both HM and SHM groups (all P>0.05). In the PSR group, BCVA improved significantly at 1 and 2y in both myopia groups (all PPP>0.05). In the RLRL group, BCVA was significantly improved at 1 and 2y, while AL shortened and SE decreased obviously from 3mo to 2y after treatment (all PP<0.05).

Conclusion

PSR and RLRL effectively improve BCVA in children with HM and SHM. PSR slows AL and SE progression, whereas RLRL reduces AL and SE, with better BCVA and AL outcomes in SHM at 1 and 2y. Both interventions are safe without severe adverse events within 2y. As a non-surgical approach, RLRL has promising clinical value.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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