Study2026Open access

Association Between Dietary Cholesterol Intake and Prediabetes: A Population-Based Study

Peng YF, Shi Z, Yin R, Xia T, Zhou Q, Yang J, Wu C

International journal of endocrinology · 0 citations

Review labels

No stated lifestyle adjustment

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cross-sectional study (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Food diaries or recalls

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2026-01-01 · Int J Endocrinol · vol. 2026 · issue 1 · p. 8722312
Publisher
Hindawi Publishing Corporation
Cited
0 citations · more than 66% of similar papers · 0.0× the field average
References
19 works
Access
Open access (journal) · CC-BY
Research areas
Diabetes, Cardiovascular Risks, and Lipoproteins · Nutritional Studies and Diet · Diet and metabolism studies
Keywords
Prediabetes, Dietary Cholesterol, Cholesterol, Logistic regression, National Health and Nutrition Examination Survey, Alcohol intake, Nutrient, Dietary fat

7 authors

From CN

  • You‐Fan PengAffiliated Hospital of Youjiang Medical University for Nationalities
  • Zihao ShiWuxi People's Hospital
  • Renjie YinWuxi People's Hospital
  • Tian XiaWuxi People's Hospital
  • Qunyan ZhouWuxi People's Hospital
  • Jiayue YangWuxi People's Hospital

Abstract

Background

Different dietary nutrients are associated with the risk of prediabetes. However, the association between dietary cholesterol intake and prediabetes is unclear. Thus, this study aimed to explore the association between dietary cholesterol intake and prediabetes.

Methods

Data were extracted and analyzed from the National Health and Nutrition Examination Survey between 2011 and 2016. Self-reported 24-hour dietary recalls were used to evaluate dietary nutrient intake.

Results

Participants with prediabetes exhibited a significantly higher dietary cholesterol intake compared with those with normoglycemia (241 [156, 367] vs. 263 [168, 381] mg, p = 0.003). Dietary cholesterol intake was significantly positively correlated with fasting blood glucose (r = 0.0607, p r = 0.0486, p = 0.007) in all participants. Multivariable logistic regression analysis showed that higher dietary cholesterol intake was independently associated with prediabetes (OR = 1.241, 95% CI: 1.010-1.525, p = 0.040; OR = 1.288, 95% CI: 1.011-1.640, p = 0.040).

Conclusion

Higher dietary cholesterol intake is independently associated with prediabetes, suggesting that dietary cholesterol intake restriction may be beneficial to prevent prediabetes.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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