LED red light therapy for relief of primary dysmenorrhea: An open, single-group target value clinical trial
Yi B, Wang D, Wei L, He J, Yu Q, Wu L, Wang Y, Wang Y, Song N, Guo L
PloS one · 0 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Industry funded
- Government
- National Key Research and Development Program of China
- Government
- National Key Research and Development Program
- Authors
- At least one author declares a financial tie to industry
- Grants
- National Key Research and Development Program of China (2017YFB0403805)
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2026-09-01 · PLoS One · vol. 21 · issue 9 · p. e0356618
- Publisher
- Public Library of Science
- Cited
- 0 citations · more than 83% of similar papers · 0.0× the field average
- References
- 8 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Menstrual Health and Disorders · Laser Applications in Dentistry and Medicine · Menopause: Health Impacts and Treatments
- Keywords
- Adverse effect, Clinical trial, Visual analogue scale, Light therapy, Red light, Randomized controlled trial
- MeSH
- humans, dysmenorrhea, pain measurement, treatment outcome, phototherapy, adult, female, young adult, red light
10 authors
From CN
- Bin Yi
- Dandan WangBaotou Medical College
- Ling Wei
- Jun He
- Qian Yu
- Lei WuBaotou Medical College
Abstract
Objective
To evaluate the efficacy and safety of LED red light therapy in alleviating primary dysmenorrhea.
Methods
A total of 119 patients with primary dysmenorrhea were enrolled in 2022. The intervention was LED red light therapy administered 7 days before menstruation. Clinical outcomes were assessed after three menstrual cycles.
Results
After three cycles of treatment, the mean reduction rate in the Visual Analog Scale (VAS) score was 63.62%. The overall effective rate of the device was 98.32%. The total score of the COX Menstrual Symptom Scale decreased by 72.93%, with specific reductions of 72.55% in symptom severity and 73.26% in pain duration. No severe adverse events were reported during the trial. Only one adverse event (0.84%) was considered device-related.
Conclusion
LED red light therapy is safe and effective for the treatment of primary dysmenorrhea.
Trial registration
ChiCTR2600116460.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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