Pharmacokinetics of caffeine during and after pregnancy
Brazier JL, Ritter J, Berland M, Khenfer D, Faucon G
Developmental pharmacology and therapeutics · 60 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2017-08-11 · Dev Pharmacol Ther · vol. 6 · issue 5 · pp. 315–322
- Publisher
- Karger Publishers
- Cited
- 157 citations · more than 99% of similar papers · 17.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 0 works
- Access
- Paywalled
- Research areas
- Pregnancy and Medication Impact · Coffee research and impacts
- Keywords
- Caffeine, Pharmacokinetics, Estriol, Pregnancy, Medicine, Metabolic clearance rate, Hormone, Post partum, Gestation, Endocrinology, Internal medicine, Physiology, Biology
- MeSH
- humans, caffeine, regression analysis, postpartum period, pregnancy, kinetics, adult, female
5 authors
From FR
- J. L. BrazierLyon 1 Université; Laboratoire de Chimie
- Jörg RitterHôpital Edouard Herriot
- Marcel Berland
- D. KhenferHôpital Edouard Herriot
- Georges FauconHôpital Edouard Herriot
Abstract
The pharmacokinetic parameters of caffeine were measured in 9 pregnant women and 4 women 4 days post partum. The results show a significant prolongation of caffeine elimination in pregnant women. Normal pharmacokinetic parameters seem to be restored as soon as 4 days post partum. Steroids hormones (estriol, estradiol, and progesterone) were measured in both cases.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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