Melatonin
Hormone supplement
Reviewed human evidence related to melatonin. Effects depend on dose and context.
Last reviewed: 2026-09-16
Aliases: None listed
Reviewed outcomes
Jet lag
Melatonin · decrease · Magnitude unknown
Melatonin may help reduce jet-lag symptoms in some travelers.
moderate evidence · Human data reviewedEvidence, caveats & sources›Chronic insomnia
Melatonin · unknown · Magnitude unknown
Evidence is not strong enough to recommend melatonin as a treatment for chronic insomnia.
limited evidence · Human data reviewedEvidence, caveats & sources›