Omega-3

Lowers triglycerides consistently; the heart-attack question is still open.

Mixed findings

High-dose EPA and DHA lower blood triglycerides in trial after trial. Whether that translates into fewer heart attacks and strokes has split the large outcome trials, and the disagreement appears to track dose, formulation and how much fish people already ate. Mood and cognition claims rest on much weaker ground.

Reviewed 2026-09-20

The papers

147 papers · 44 reviews or meta-analyses · 147 in humans · 2016–2026

Official sources

NIH ODS — Omega-3 fatty acids fact sheetOpen ↗Browse the literature on PubMedOpen ↗

Reviewed ingredient

This topic is also a reviewed ingredient, with dose context and claim-level evidence.

Open the omega-3 ingredient page›

How this list was built

We searched Europe PMC for English-language papers published since 2016 whose title contains “omega-3” or “fish oil” or “eicosapentaenoic” or “docosahexaenoic”, kept meta-analyses, systematic reviews and randomised trials, then ranked them by study design first, then recency and citations. Retracted papers are removed.

Open a paper to read its abstract and ask for an AI brief of what it found.

Educational information about published research. Not medical advice, and not a recommendation to start or stop anything.