Creatine

The most studied sports supplement there is.

Well supported

Creatine monohydrate reliably improves performance in short, intense efforts such as lifting and sprinting, and that finding has held up across dozens of randomised trials and several meta-analyses. Trials typically use 3–5 g per day, with or without a loading week. Claims beyond exercise — cognition, mood, muscle preservation in older adults — are actively studied but far less settled than the performance results.

Reviewed 2026-09-20

The papers

176 papers · 35 reviews or meta-analyses · 176 in humans · 2015–2026

Official sources

NIH ODS — Dietary supplements for exercise and performanceOpen ↗Browse the literature on PubMedOpen ↗

Reviewed ingredient

This topic is also a reviewed ingredient, with dose context and claim-level evidence.

Open the creatine ingredient page›

How this list was built

We searched Europe PMC for English-language papers published since 2015 whose title contains “creatine” or “creatine monohydrate”, kept meta-analyses, systematic reviews and randomised trials, then ranked them by study design first, then recency and citations. Retracted papers are removed.

Open a paper to read its abstract and ask for an AI brief of what it found.

Educational information about published research. Not medical advice, and not a recommendation to start or stop anything.